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Atrial signal amplitude in healthy subjects and patients with atrial fibrillation from the 12-lead ECG

Lookup NU author(s): Dr Philip Langley, Emeritus Professor Alan MurrayORCiD


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The atrial electrical signal or P wave is becoming more widely studied because of the large incidence of atrial arrhythmias. There are few reports quantifying the spatial distribution of atrial signal amplitude in the 12-lead ECG. Our aims were to quantify the spatial distribution of atrial signal amplitudes in groups of healthy subjects and patients with atrial fibrillation, and to develop a simple model of atrial depolarisation based on a single dipole. Amplitude was significantly smaller (p < 0.05) in leads I, II, aV R, aVF, V5 and V6, and significantly larger in lead VI in atrial fibrillation compared with those of the healthy group. A single dipole model was able to qualitatively simulate the body surface atrial electrical signal in specific subjects from these groups. © 2004 IEEE.

Publication metadata

Author(s): Langley P, Murray A

Publication type: Conference Proceedings (inc. Abstract)

Publication status: Published

Conference Name: Computers in Cardiology

Year of Conference: 2004

Pages: 421-424

ISSN: 0276-6574

Publisher: IEEE


DOI: 10.1109/CIC.2004.1442963