Toggle Main Menu Toggle Search

Open Access padlockePrints

Molecular Epidemiology of Spinocerebellar Ataxia Type 6

Lookup NU author(s): Kate Craig, Sharon Foster, Dr Ann Curtis, Professor Patrick Chinnery

Downloads

Full text for this publication is not currently held within this repository. Alternative links are provided below where available.


Abstract

We performed a population-based clinical and molecular genetic study of spinocerebellar ataxia type 6 (SCA6) in the northeast of England. The minimum point prevalence of SCA6 was 1.59 in 100,000 (95% confidence interval [CI], 1.04-2.14), and the number of individuals who either had SCA6 or are at risk of developing SCA6 was at least 5.21 in 100,000 (95% CI, 4.31-6.10), or 1 in 19,210. Microsatellite analysis of the CACNA1A gene indicated a founder effect for SCA6 within this region.


Publication metadata

Author(s): Craig K, Keers SM, Archibald K, Curtis A, Chinnery PF

Publication type: Article

Publication status: Published

Journal: Annals of Neurology

Year: 2004

Volume: 55

Issue: 5

Pages: 752-755

ISSN (print): 0364-5134

ISSN (electronic): 1531-8249

Publisher: John Wiley & Sons, Inc.

URL: http://dx.doi.org/10.1002/ana.20110

DOI: 10.1002/ana.20110

PubMed id: 15122720


Altmetrics

Altmetrics provided by Altmetric


Share