Browse by author
Lookup NU author(s): Dr Gilles Borrelly,
Dr Clive Butler,
Professor Nigel Robinson
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
The thylakoid lumen of the cyanobacterium Synechocystis PCC 6803 is supplied with copper via two copper-transporting ATPases anc a metallochaperone intermediary. We show that the copper site of this metallochaperone is unusual and consists of two cysteine residues and a histidine imidazole located on structurally dynamic loops. Substitution of this histidine residue enhances bacterial two-hybrid interaction with the cytosolic copper exporter, but not the copper importer, suggesting that the interacting surfaces are distinct, with implications for metal transfer.
Author(s): Borrelly GPM, Blindauer CA, Schmid R, Butler CS, Cooper CE, Harvey I, Sadler PJ, Robinson NJ
Publication type: Article
Publication status: Published
Journal: Biochemical Journal
Print publication date: 01/03/2004
ISSN (print): 0264-6021
ISSN (electronic): 1470-8728
Publisher: The Biochemical Society
PubMed id: 14711369
Altmetrics provided by Altmetric