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Asymmetric carbon-carbon bond formation. Use of CACHy™ catalysts to produce optically active cyanohydrins

Lookup NU author(s): Professor Michael North


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Catalytic asymmetric synthesis of cyanohydrins using CACHy™ catalysts, made of oxo-titanium or vanadium coordinated with salen ligands, provides products such as alpha-hydroxy acids and beta-amino alcohols efficiently and with high optical purity. Several processes have been developed and shown to be scaleable, economic and robust.

Publication metadata

Author(s): Blacker AJ, North M, Belokon YN

Publication type: Article

Publication status: Published

Journal: Chimica Oggi

Year: 2004

Volume: 22

Issue: 11-12

Pages: S30-S32

Print publication date: 01/11/2004

ISSN (print): 0392-839X

ISSN (electronic): 1973-8250

Publisher: Tekno Scienze