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The effect of contrast reduction on pattern-reversal VEPs in suspected multiple sclerosis and optic neuritis

Lookup NU author(s): Dr Keith Mitchell

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Abstract

A retrospective study was conducted to investigate whether the use of low-contrast stimuli in addition to the standard high-contrast stimuli would increase the sensitivity of the pattern-reversal P100 when testing for multiple sclerosis (MS) and optic neuritis (ON). We found that there was a statistically significant increase in the number of abnormal results when using 25′ checks, but not for 50′ checks. Examination of patient records showed that VEP abnormalities to low-contrast stimuli only was not prognostic for subsequent development of multiple sclerosis. © Springer 2005.

Publication metadata

Author(s): Davidson AW, Scott RF, Mitchell KW

Publication type: Article

Publication status: Published

Journal: Documenta Ophthalmologica

Year: 2004

Volume: 109

Issue: 2

Pages: 157-161

ISSN (print): 0012-4486

ISSN (electronic): 1573-2622

Publisher: Springer

URL: http://dx.doi.org/10.1007/s10633-004-3831-9

DOI: 10.1007/s10633-004-3831-9

PubMed id: 15881261

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