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Ontology for genome comparison and genomic rearrangements

Lookup NU author(s): Dr Keith Flanagan, Dr Matthew Pocock, Professor Pete Lee, Professor Anil Wipat


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We present an ontology for describing genomes, genome comparisons, their evolution and biological function. This ontology will support the development of novel genome comparison algorithms and aid the community in discussing genomic evolution. It provides a framework for communication about comparative genomics, and a basis upon which further automated analysis can be built. The nomenclature defined by the ontology will foster clearer communication between biologists, and also standardize terms used by data publishers in the results of analysis programs. The overriding aim of this ontology is the facilitation of consistent annotation of genomes through computational methods, rather than human annotators. To this end, the ontology includes definitions that support computer analysis and automated transfer of annotations between genomes, rather than relying upon human mediation. Copyright © 2004 John Wiley & Sons, Ltd.

Publication metadata

Author(s): Flanagan K, Stevens R, Pocock M, Lee P, Wipat A

Publication type: Conference Proceedings (inc. Abstract)

Publication status: Published

Conference Name: 7th Annual Bio-Ontologies Meeting

Year of Conference: 2004

Pages: 537-544

Publisher: Comparative and Functional Genomics


DOI: 10.1002/cfg.436