Toggle Main Menu Toggle Search

Open Access padlockePrints

6-Methyl-2-pyridone pentahydrate

Lookup NU author(s): Emeritus Professor Bill CleggORCiD, Gary Nichol


Full text for this publication is not currently held within this repository. Alternative links are provided below where available.


Crystals of the title compound, C6H7NO·5H 2O, were grown over a period of several weeks from an aqueous solution of the commercial compound. The molecule crystallizes in space group P1̄ and there are two independent 6-methyl-2-pyridone (Hmhp) molecules in the asymmetric unit, together with ten molecules of water. Packing diagrams reveal stacks of hydrogen-bonded Hmhp dimers surrounded by channels of water molecules. The Hmhp molecules pack with face-to-face π-π stacking, a common feature of pyridone crystal structures. Each water molecule serves twice as hydrogen-bond donor and twice as acceptor, and is thus pseudo-tetrahedral. The water molecules are arranged in hydrogen-bonded five- and six-membered rings and the rings are fused together, with the five-membered rings adopting an envelope conformation and the six-membered rings adopting either a chair or boat conformation. This structure is further evidence that Hmhp exists in the solid state as the pyridone tautomer and not the pyridinol tautomer. © 2004 International Union of Crystallography Printed in Great Britain - all rights reserved.

Publication metadata

Author(s): Clegg W, Nichol GS

Publication type: Article

Publication status: Published

Journal: Acta Crystallographica Section E: Structure Reports Online

Year: 2004

Volume: 60

Issue: 8

Pages: o1433-o1436

Print publication date: 01/08/2004

ISSN (electronic): 1600-5368

Publisher: Wiley-Blackwell


DOI: 10.1107/S1600536804018367


Altmetrics provided by Altmetric