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Asymmetric synthesis of polymer-supported cyanohydrin acetates

Lookup NU author(s): Professor Michael North

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Abstract

A bimetallic titanium(salen) complex has been used to catalyze the asymmetric addition of potassium cyanide to aldehydes attached to Wang resin giving polymer supported cyanohydrin propionates with up to 91% enantiomeric excesses. © 2005 Elsevier Ltd. All rights reserved.

Publication metadata

Author(s): Belokon' YN, Carta P, North M

Publication type: Article

Publication status: Published

Journal: Tetrahedron Letters

Year: 2005

Volume: 46

Issue: 26

Pages: 4483-4486

Print publication date: 27/06/2005

ISSN (print): 0040-4039

ISSN (electronic): 1873-3581

Publisher: Elsevier

URL: http://dx.doi.org/10.1016/j.tetlet.2005.04.109

DOI: 10.1016/j.tetlet.2005.04.109

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