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A prospective, randomised controlled trial comparing the efficacy of pre-oxygenation in the 20° head-up vs supine position

Lookup NU author(s): Dr David Saunders, Anthony Hildreth


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We investigated whether positioning patients undergoing general anaesthesia for cholecystectomy in a 20° head-up position, as opposed to supine, improved the efficacy of 3 mm of standard pre-oxygenation via a circle breathing system. Following pre-oxygenation, patients received a standard induction of anaesthesia and the apnoea time (from administration of rocuronium to the arterial oxygen saturation to fall to 95%) was recorded. Mean (95% CI) apnoea time was 386 (343-429) sin the 20° head-up position (n = 17) vs 283 (243-322) s in the supine position (n = 18; p = 0.002). Pre-oxygenation is significantly more efficacious and by inference more efficient in the 20° head-up position than in the supine position. © 2005 Blackwell Publishing Ltd.

Publication metadata

Author(s): Lane S, Saunders D, Schofield A, Padmanabhan R, Hildreth A, Laws D

Publication type: Article

Publication status: Published

Journal: Anaesthesia

Year: 2005

Volume: 60

Issue: 11

Pages: 1064-1067

Print publication date: 01/11/2005

ISSN (print): 0003-2409

ISSN (electronic): 1365-2044

Publisher: Wiley


DOI: 10.1111/j.1365-2044.2005.04374.x

PubMed id: 16229689


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