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Electrochemical impedance spectroscopy studies of polymer degradation: Application to biosensor development

Lookup NU author(s): Dr Cesar Fernandez-Sanchez, Emeritus Professor Calum McNeilORCiD

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Abstract

Electrochemical impedance spectroscopy (EIS) has emerged as a useful analytical tool for the development of sensor devices in a wide variety of configurations. We focus this review on the particular application of EIS to the study of degradation phenomena taking place at polymer-coated substrates, which have primarily been of great interest in the study of corrosion protection; more recently, it has led to the successful construction of versatile polymer-coated transducers for sensor development. Impedance analysis of breakdown processes of polymer coatings on electrochemical transducers through the direct or indirect action of biomolecules constitutes a feasible detection protocol for the fabrication of generic integrated biosensors. We give a detailed description of such applications, and present a particular view on sensor devices reported so far and ideas that bring significant improvements to this promising technology. © 2004 Elsevier Ltd. All rights reserved.


Publication metadata

Author(s): Fernandez-Sanchez C, McNeil CJ, Rawson K

Publication type: Review

Publication status: Published

Journal: Trends in Analytical Chemistry

Year: 2005

Volume: 24

Issue: 1

Pages: 37-48

ISSN (print): 0165-9936

ISSN (electronic):

URL: http://dx.doi.org/10.1016/j.trac.2004.08.010

DOI: 10.1016/j.trac.2004.08.010


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