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Does donor cardiopulmonary resuscitation time affect outcome in uncontrolled non-heart-beating donor renal transplants?

Lookup NU author(s): John Asher, Professor Colin Wilson, Muhammed Gok, Dr Brian Shenton, Basav Sen, Bryon Jaques, Professor Naeem Soomro, David Rix, Professor Derek Manas, David Talbot


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Uncontrolled non-heart-beating donors offer the opportunity to significantly expand the potential pool of kidney donors but are associated with a variable duration of cardiopulmonary resuscitation (CPR), where cardiac output is only 30% to 40% of normal. We were concerned that prolonged CPR would adversely affect the function of transplanted kidneys. In our series of 46 uncontrolled donors the mean duration of CPR was 60 minutes, which also represents a realistic cutoff point for CPR duration. Taking a cutoff point of 60 minutes, we found no differences in kidney discard rates following viability assessment, primary nonfunction rate, or duration of delayed graft function. We therefore conclude that if formal viability assessment is performed, kidneys may be retrieved from uncontrolled non-heart-beating donors irrespective of duration of CPR. © 2005 by Elsevier Inc. All rights reserved.

Publication metadata

Author(s): Asher JF, Navarro A, Watson J, Wilson CH, Robson L, Gupta A, Gok MA, Balupuri S, Shenton BK, Del Rio Martin J, Sen B, Jaques BC, Soomro NA, Rix DA, Manas DM, Talbot D

Publication type: Conference Proceedings (inc. Abstract)

Publication status: Published

Conference Name: 22nd Congress of the Scandinavian Transplantation Society

Year of Conference: 2004

Pages: 3264-3265

ISSN: 0041-1345

Publisher: Transplantation Proceedings: Elsevier


DOI: 10.1016/j.transproceed.2005.09.006

PubMed id: 16298567