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Association between mild vascular cognitive impairment and impaired activities of daily living in older stroke survivors without dementia

Lookup NU author(s): Dr Sally Stephens, Professor Raj KalariaORCiD, Ruth Pearce, Dr Clive Ballard


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OBJECTIVES: To determine the relationship between mild vascular cognitive impairment (mVCI) and functional disability in older stroke survivors without dementia. DESIGN: Cohort study. SETTING: Stroke patients from representative hospital-based stroke registers. PARTICIPANTS: Three hundred thirty-nine stroke survivors without dementia, aged 75 and older. MEASUREMENTS: Neuropsychological assessments were completed 3 months poststroke. Activities of daily living (ADLs) were evaluated using the Bristol scale. Operationalized criteria, including cognitive impairment no dementia (CIND), were applied for mVCI. RESULTS: Significant impairments of ADLs were evident in mVCI (CIND vs no CIND; basic care: z = 3.2; P = .001, intermediate care: z = 3.6; P < .001, complex management: z = 4.5; P < .001) but varied according to the profile of cognitive impairments. Patients with attentional or global impairments had more severe functional disability than patients with isolated memory deficits, with an intermediate level of dysfunction in patients with executive impairments. CONCLUSION: The findings emphasize the importance of identifying early cognitive impairments to optimize rehabilitation, care planning, and secondary prevention of dementia in stroke patients. © 2005 by the American Geriatrics Society.

Publication metadata

Author(s): Stephens S, Kenny RA, Rowan E, Kalaria RN, Bradbury M, Pearce R, Wesnes K, Ballard CG

Publication type: Article

Publication status: Published

Journal: Journal of the American Geriatrics Society

Year: 2005

Volume: 53

Issue: 1

Pages: 103-107

Print publication date: 01/01/2005

ISSN (print): 0002-8614

ISSN (electronic): 1532-5415

Publisher: Wiley


DOI: 10.1111/j.1532-5415.2005.53019.x

PubMed id: 15667385


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