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Postmortem diagnosis of chronic granulomatous disease: How worthwhile is it?

Lookup NU author(s): Sue Bruce, Dr David Spencer, Dr David Crawford, Dr Angela Galloway, Dr Nigel Cooper, Dr Terence Flood, Dr Mario Abinun


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A previously healthy 11 year old boy died unexpectedly after a rapid course of progressive pneumonia. Postmortem microbiology and histopathology suggested an underlying diagnosis of chronic granulomatous disease. This was confirmed by neutrophil oxidative burst and gene mutation analysis of other family members, one of whom benefited from early bone marrow transplantation.

Publication metadata

Author(s): Lakshman R, Bruce S, Spencer DA, Crawford D, Galloway A, Cooper PN, Barge D, Roos D, Flood TJ, Abinun M

Publication type: Article

Publication status: Published

Journal: Journal of Clinical Pathology

Year: 2005

Volume: 58

Issue: 12

Pages: 1339-1341

ISSN (print): 0021-9746

ISSN (electronic): 1472-4146

Publisher: BMJ Group


DOI: 10.1136/jcp.2004.025098

PubMed id: 16311362


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