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Lookup NU author(s): Mr TF Anderson Anderson,
Dr Matthew Statham,
Dr Michael Carroll
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Silanediols have been shown to be effective bioisosteres for the hydrated carbonyl group. Current methods for the formation of silanediols place a number of constraints on how and where this functionality may be used. A range of arylsilanes that would allow both the formation of arylsilanediols and that are also compatible with multi-step synthetic routes, have been investigated as possible precursors to silanediols. Through this study bis(2-furyl)silanes and, in particular, bis(2-thienyl)silanes have been identified as practical precursors to arylsilanediols. © 2006 Elsevier Ltd. All rights reserved.
Author(s): Anderson TF, Statham MAJ, Carroll MA
Publication type: Article
Publication status: Published
Journal: Tetrahedron Letters
ISSN (print): 0040-4039
ISSN (electronic): 1873-3581
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