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Lookup NU author(s): Stefanie Baur,
Professor Michael Goodfellow,
Emeritus Professor Alan Ward
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Three new members of the fluostatin family, fluostatins C-E, were discovered in a culture filtrate extract of strain Acta 1383 during an HPLC screening program. The producing strain belongs to the genus Streptomyces and is closely related to type strains classified in the Streptomyces lavendulae 16S rRNA subclade. Fluostatins are named by their characteristic fluorenone chromophore. Fluostatin C shows moderate activity against selected human tumor cell lines. © Japan Antibiotics Research Association.
Author(s): Baur S, Niehaus J, Karagouni AD, Katsifas EA, Chalkou K, Meintanis C, Jones AL, Goodfellow M, Ward AC, Beil W, Schneider K, Sussmuth RD, Fiedler H-P
Publication type: Article
Publication status: Published
Journal: Journal of Antibiotics
Print publication date: 01/05/2006
ISSN (print): 0021-8820
ISSN (electronic): 1881-1469
Publisher: Nature Publishing Group
PubMed id: 16883779
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