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Magnetic resonance imaging abnormalities in young euthymic patients with bipolar affective disorder

Lookup NU author(s): Dr David Cousins, Dr Sean Parker, Dr Victor McAllister, Emeritus Professor Nicol Ferrier, Dr Brian Moore


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Temporal lobe and limbic structures may be abnormal in bipolar disorder. T2-weighted magnetic resonance imaging (MRI) scans frequently show deep white matter lesions. MRI was performed on 50 young (19-39 years) euthymic patients with bipolar disorder and 26 controls. Mean temporal lobe volumes were reduced in patients (right, 9.42 cm3; left, 6.33 cm3) but this could not be ascribed to a specific structure. Deep white matter lesions were present in 5 patients but no controls raising questions of their aetiological significance.

Publication metadata

Author(s): El-Badri SM, Cousins DA, Parker S, Ashton HC, McAllister VL, Ferrier IN, Moore PB

Publication type: Article

Publication status: Published

Journal: British Journal of Psychiatry

Year: 2006

Volume: 189

Pages: 81-82

ISSN (print): 0007-1250

ISSN (electronic): 1472-1465

Publisher: Royal College of Psychiatrists


DOI: 10.1192/bjp.bp.105.011098


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