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Lookup NU author(s): Dr David Cousins,
Dr Sean Parker,
Dr Victor McAllister,
Emeritus Professor Nicol Ferrier,
Dr Brian Moore
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Temporal lobe and limbic structures may be abnormal in bipolar disorder. T2-weighted magnetic resonance imaging (MRI) scans frequently show deep white matter lesions. MRI was performed on 50 young (19-39 years) euthymic patients with bipolar disorder and 26 controls. Mean temporal lobe volumes were reduced in patients (right, 9.42 cm3; left, 6.33 cm3) but this could not be ascribed to a specific structure. Deep white matter lesions were present in 5 patients but no controls raising questions of their aetiological significance.
Author(s): El-Badri SM, Cousins DA, Parker S, Ashton HC, McAllister VL, Ferrier IN, Moore PB
Publication type: Article
Publication status: Published
Journal: British Journal of Psychiatry
ISSN (print): 0007-1250
ISSN (electronic): 1472-1465
Publisher: Royal College of Psychiatrists
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