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Correction of neuromuscular scoliosis in patients with preexisting respiratory failure

Lookup NU author(s): Dr Inderbir Gill, Dr Michelle Eagle, Emerita Professor Katherine Bushby, Dr Robert Bullock


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STUDY DESIGN. A prospective observational study in scoliosis patients who were on noninvasive night ventilation for respiratory failure. OBJECTIVE. To report the results of spinal deformity correction in a group of patients with progressive scoliosis and rare forms of muscular dystrophy/myopathy with respiratory failure who were on nocturnal ventilatory support at the time of surgery. SUMMARY OF BACKGROUND DATA. This is the first study on the results of deformity correction in a series of patients on ventilatory support. MATERIALS AND METHODS. Eight patients (6 males, 2 females) presented with progressive scoliosis and respiratory failure. The mean age at surgery was 12 years (range, 8-15 years). The mean follow-up was 48 months (range, 12-80 months). Outcome measures include lung function (spirometry), overnight pulse oximetry, Cobb angles, duration of stay in Intensive care (ICU), and the total hospital stay. RESULTS. The mean stay in the ICU was 2.7 days (range, 2-5 days). The mean hospital stay was 14.2 days (range, 10-21 days). The mean preoperative Cobb angle was 70.2° (55°-85°). This changed to 32° (16°-65°) after surgery (P = 0.0002). The mean vital capacity at the time of surgery was 20% (range, 13%-28%). The mean vital capacity of patients at last follow-up was 18% (range, 10%-31%). The desaturation noted on the preventilation overnight oximetry was reversed by nocturnal ventilation. All patients recovered well following surgery with no major cardiac or pulmonary complications. CONCLUSION. Patients with preexisting respiratory failure on nocturnal noninvasive ventilation can be safely operated for deformity correction. This can help to significantly improve their quality of life. © 2006 Lippincott Williams & Wilkins, Inc.

Publication metadata

Author(s): Gill I, Eagle M, Mehta JS, Gibson MJ, Bushby K, Bullock R

Publication type: Article

Publication status: Published

Journal: Spine

Year: 2006

Volume: 31

Issue: 21

Pages: 2478-2483

ISSN (print): 0362-2436

ISSN (electronic): 1528-1159

Publisher: Lippincott Williams & Wilkins


DOI: 10.1097/01.brs.0000239215.87174.8f


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