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Lookup NU author(s): Professor David Burn,
Dr Liesl Allcock,
Dr John Davison,
Professor Patrick Chinnery
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A genetic susceptibility to depression in PD, acting via the serotonergic system, has been suggested. We examined the influence of allelic variation (L/S) in a functional polymorphism in the serotonin transporter (5-HTTLPR) gene upon mood in 108 PD patients and 82 controls. Using a logistic regression model we found no evidence for an association between 5-HTTLPR genotypes, or the presence of the S allele, and depression. © 2006 Elsevier Ltd. All rights reserved.
Author(s): Burn DJ, Tiangyou W, Allcock LM, Davison J, Chinnery PF
Publication type: Article
Publication status: Published
Journal: Parkinsonism & Related Disorders
ISSN (print): 1353-8020
ISSN (electronic): 1873-5126
PubMed id: 16459126
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