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Control of mRNA stability in eukaryotes

Lookup NU author(s): Dr Sarah Newbury

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Abstract

mRNA turnover plays a key role in the control of gene expression. Recent work has shown that proteins involved in mRNA turnover are located in multicomponent complexes which are tightly regulated. The control of mRNA stability is also intimately linked with translational processes. This article reviews the pathways and enzymes that control mRNA turnover in eukaryotic cells and discusses their mechanisms of control. ©2006 Biochemical Society.

Publication metadata

Author(s): Newbury SF

Publication type: Article

Publication status: Published

Journal: Biochemical Society Transactions

Year: 2006

Volume: 34

Issue: 1

Pages: 30-34

ISSN (print): 0300-5127

ISSN (electronic): 1470-8752

Publisher: Portland Press Ltd.

URL: http://dx.doi.org/10.1042/BST0340030

DOI: 10.1042/BST0340030

PubMed id: 16246172

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