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Lookup NU author(s): Thierry Achard,
Professor Michael North,
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N,N-Diphenyl-α-haloacetamides undergo Darzens condensations with aldehydes under heterogeneous reaction conditions in the presence of a metal hydroxide base. By appropriate choice of solvent, base and halide, very high diastereoselectivities favouring formation of the cis- or trans-epoxide can be obtained. © 2007 Elsevier Ltd. All rights reserved.
Author(s): Achard TJR, Belokon' YN, Hunt J, North M, Pizzato F
Publication type: Article
Publication status: Published
Journal: Tetrahedron Letters
ISSN (print): 0040-4039
ISSN (electronic): 1873-3581
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