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Mitochondrial DNA Transcription: Regulating the Power Supply

Lookup NU author(s): Professor Robert Taylor, Emeritus Professor Doug Turnbull


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In this issue of Cell, Park et al. (2007) describe the nuclear encoded protein MTERF3 as a negative regulator of mitochondrial DNA transcription initiation. This study highlights a mechanism by which mitochondrial DNA transcription (and therefore oxidative phosphorylation) may be regulated in response to alterations in the cell's physiological and metabolic demands. © 2007 Elsevier Inc. All rights reserved.

Publication metadata

Author(s): Taylor RW, Turnbull DM

Publication type: Note

Publication status: Published

Journal: Cell

Year: 2007

Volume: 130

Issue: 2

Pages: 211-213

ISSN (print): 0092-8674

ISSN (electronic): 1097-4172


DOI: 10.1016/j.cell.2007.07.002