Toggle Main Menu Toggle Search

Open Access padlockePrints

Life-years-gained from population risk factor changes and modern cardiology treatments in Ireland

Lookup NU author(s): Professor Julia Critchley


Full text for this publication is not currently held within this repository. Alternative links are provided below where available.


Background: Coronary heart disease (CHD) mortality rates in Ireland have halved since the mid-1980s, and adult life expectancy has also steadily improved. This study estimated the life-years-gained by CHD treatments and by changes in cardiovascular risk factor levels. Methods: A previously validated Irish IMPACT CHD mortality model was used to integrate large amounts of data on (i) patient numbers, (ii) treatment uptake, (iii) risk factor trends, (iv) effectiveness of cardiology treatments and risk factor reductions, and (v) median survival in patients with and without CHD, all stratified by age and sex. Results were tested in rigorous sensitivity analyses. Results: There were 3763 fewer CHD deaths than expected in 2000 compared with the base year, 1985. This resulted in ∼44 060 life-years-gained among people aged 25-84. Specific medical and surgical treatments given in 2000 for CHD patients together gained ∼14 505 life-years. Population changes in cholesterol and smoking levels accounted for some 32 705 life-years-gained, 66% from reductions in cholesterol alone. Adverse changes in obesity and diabetes resulted in a loss of ∼3670 life-years. Conclusions: Use of modern cardiology treatments in Ireland from 1985 to 2000 gained many thousands of life-years. However, twice as many life-years were generated by relatively modest reductions in major risk factors. Effective policies, such as the promotion of healthy diets, and weight reduction, together with the recent nationwide workplace smoking ban, will be essential to maintain and further enhance health gain. © The Author 2006. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

Publication metadata

Author(s): Kabir Z, Bennett K, Shelley E, Unal B, Critchley J, Feely J, Capewell S

Publication type: Article

Publication status: Published

Journal: European Journal of Public Health

Year: 2007

Volume: 17

Issue: 2

Pages: 193-198

Print publication date: 01/04/2007

ISSN (print): 1101-1262

ISSN (electronic): 1464-360X

Publisher: Oxford University Press


DOI: 10.1093/eurpub/ckl090

PubMed id: 16798782


Altmetrics provided by Altmetric