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Lookup NU author(s): Dr Amy Reeve,
Emeritus Professor Doug Turnbull
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A decline in mitochondrial function has long been shown to exist in neurodegenerative disease. Whether this decline is a secondary consequence of other factors or whether it causes the eventual death of a cell is unknown. In this review, we will discuss some of the major evidence surrounding mitochondrial DNA mutations leading to mitochondrial dysfunction in neurodegenerative disease and discuss their possible role in neurodegeneration. ©The Authors.
Author(s): Krishnan KJ, Reeve AK, Turnbull DM
Publication type: Conference Proceedings (inc. Abstract)
Publication status: Published
Conference Name: Biochemical Society Transactions: Focus Topics at Life Sciences
Year of Conference: 2007
Publisher: Portland Press Ltd.
PubMed id: 17956320
Library holdings: Search Newcastle University Library for this item