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The Newcastle University research output collection, currently available on ePrints, will shortly be moving to a new open repository platform, Figshare. To prepare for the data migration we have paused adding new content to ePrints, and will resume once the new repository is launched. During this time you will continue to have access to ePrints (but no new content will appear). We will share updates here when available.

Plasmid segregation: Spatial awareness at the molecular level

Lookup NU author(s): Professor Kenn Gerdes

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Abstract

In bacteria, low-copy number plasmids ensure their stable inheritance by partition loci (par), which actively distribute plasmid replicates to each side of the cell division plane. Using time-lapse fluorescence microscopic tracking of segregating plasmid molecules, a new study provides novel insight into the workings of the par system from Escherichia coli plasmid R1. Despite its relative simplicity, the plasmid partition spindle shares characteristics with the mitotic machinery of eukaryotic cells. © The Rockefeller University Press.

Publication metadata

Author(s): Moller-Jensen J, Gerdes K

Publication type: Review

Publication status: Published

Journal: Journal of Cell Biology

Year: 2007

Volume: 179

Issue: 5

Pages: 813-815

Print publication date: 03/12/2007

ISSN (print): 0021-9525

ISSN (electronic): 1540-8140

URL: http://dx.doi.org/10.1083/jcb.200710192

DOI: 10.1083/jcb.200710192

PubMed id: 18039938

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