Browse by author
Lookup NU author(s): Thierry Achard,
Professor Michael North,
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
A cobalt(salen) complex has been shown to catalyse the asymmetric Darzens condensation between α-haloamides and aldehydes, allowing both the relative and absolute stereochemistry of the epoxy-amide products to be controlled. Under optimal conditions, cis-epoxides can be obtained diastereoselectively with up to 50% enantiomeric excess, whilst by changing the leaving group and base, trans-epoxides can be produced diastereoselectively with up to 43% enantiomeric excess. © 2007 Elsevier Ltd. All rights reserved.
Author(s): Achard TJR, Belokon' YN, Ilyin M, Moskalenko M, North M, Pizzato F
Publication type: Article
Publication status: Published
Journal: Tetrahedron Letters
ISSN (print): 0040-4039
ISSN (electronic): 1873-3581
Altmetrics provided by Altmetric