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A more discerning zinc exporter

Lookup NU author(s): Professor Nigel Robinson


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An emerging view is that high-fidelity metal selection by the proteins involved in metal homeostasis is pivotal to ensure that the correct metals bind to nascent metalloproteins. A new study demonstrates that the AztA zinc exporter performs this function by using tandem metal-binding domains to entrap some of the wrong metals in nonproductive complexes. © 2007 Nature Publishing Group.

Publication metadata

Author(s): Robinson NJ

Publication type: Note

Publication status: Published

Journal: Nature Chemical Biology

Year: 2007

Volume: 3

Issue: 11

Pages: 692-693

ISSN (print): 1552-4450

ISSN (electronic): 1552-4469


DOI: 10.1038/nchembio1107-692

PubMed id: 17948015