Browse by author
Lookup NU author(s): Professor Andrew Jackson
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
We describe a small, chronically implantable microwire array for obtaining long-term unit recordings from the cortex of unrestrained nonhuman primates. After implantation, the depth of microwires can be individually adjusted to maintain large-amplitude action potential recordings from single neurons over many months. We present data recorded from the primary motor cortex of two monkeys by autonomous on-board electronic circuitry. Waveforms of individual neurons remained stable for recording periods of several weeks during unrestrained behavior. Signal-to-noise ratios, waveform stability, and rates of cell loss indicate that this method may be particularly suited to experiments investigating the neural correlates of processes extending over multiple days, such as learning and plasticity. Copyright © 2007 The American Physiological Society.
Author(s): Jackson A, Fetz EE
Publication type: Article
Publication status: Published
Journal: Journal of Neurophysiology
ISSN (print): 0022-3077
ISSN (electronic): 1522-1598
Publisher: American Physiological Society
PubMed id: 17855584
Altmetrics provided by Altmetric