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Vasovagal Syncope in the Older Patient

Lookup NU author(s): Dr Maw Tan, Dr Steve Parry


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Vasovagal syncope (VVS) has been diagnosed with increasing frequency in older patients since the head-up tilt-table test (HUT) was described over 2 decades ago. The incidence and prevalence of VVS in this age group remains unknown. Older individuals are more likely to display a dysautonomic hemodynamic pattern with a predominantly hypotensive response during HUT. The positivity rates to passive and isoprotenerol-provoked HUT are reduced with age, but positivity rates for glyceryl-trinitrate-induced HUT are comparable with younger subjects. Few studies into treatment strategies have included older subjects. This is a review of the existing literature on the epidemiology, clinical characteristics, diagnostic tools, and treatment strategies for VVS in older patients, highlighting important areas for future research. © 2008 American College of Cardiology Foundation.

Publication metadata

Author(s): Tan MP, Parry SW

Publication type: Article

Publication status: Published

Journal: Journal of the American College of Cardiology

Year: 2008

Volume: 51

Issue: 6

Pages: 599-606

ISSN (print): 0735-1097

ISSN (electronic): 1558-3597

Publisher: Elsevier Inc.


DOI: 10.1016/j.jacc.2007.11.025

PubMed id: 18261677


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Funder referenceFunder name
DMT_RCP/DMT 1ST ROUND (5)The Dunhill Medical Trust