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Antipsychotic-induced hyperprolactinemia and delusion of pregnancy

Lookup NU author(s): Dr Niraj Ahuja, Dr Stephen Moorhead, Dr Adrian Lloyd, Dr Andrew Cole


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The authors describe 12 patients with antipsychotic-induced hyperprolactinemia. Six patients had erroneous ideas of being pregnant (four delusional and two non-delusional) temporally associated with hyperprolactinemia and resolving as prolactin levels returned to normal. The remaining six patients did not develop such ideas. Contrasting the clinical features of the two groups of patients in the context of existing literature informs on the possible biological and cognitive mechanisms that can be hypothesized to underlie the relationship between hyperprolactinemia due to antipsychotics and the development of inaccurate beliefs and feelings about pregnancy, and the effect of current mental state on the propensity to develop these beliefs. © 2008 The Academy of Psychosomatic Medicine.

Publication metadata

Author(s): Ahuja N, Moorhead SRJ, Lloyd AJ, Cole AJ

Publication type: Article

Publication status: Published

Journal: Psychosomatics

Year: 2008

Volume: 49

Issue: 2

Pages: 163-167

Print publication date: 01/03/2008

ISSN (print): 0033-3182

ISSN (electronic): 1545-7206

Publisher: American Psychiatric Publishing, Inc.


DOI: 10.1176/appi.psy.49.2.163

PubMed id: 18354070


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