Toggle Main Menu Toggle Search

Open Access padlockePrints

Mucoepidermoid carcinoma of the head and neck: A 13-year review

Lookup NU author(s): Dr Shaheel Chummun, Neil McLean, Dr Charles Kelly


Full text for this publication is not currently held within this repository. Alternative links are provided below where available.


Mucoepidermoid carcinoma (MEC) is a malignant tumour arising from salivary gland tissue. The aim of this study was to review the management of MEC at one institution over a period of 13 years and to identify factors associated with morbidity and mortality. The case notes of patients with MEC treated between 1987 and 2000 were reviewed. Well-differentiated tumours were graded as low grade tumours and poorly differentiated tumours as high grade. Staging was done according to the TMN classification of the American Joint Committee on Cancer (AJCC).The collected data were analysed using GraphPad Prism 4.03. The Kaplan-Meier method and the Logrank Test were used to assess the statistical significance of various groups. There were 37 patients identified. Twenty-one cases were low grade tumours and sixteen high grade. The overall survival rate at 5 and 10 years was 74.8 and 65.2%, respectively. The overall loco-regional control rates at 5 and 10 years were 87.3 and 60.4%, respectively. High grade, high stage and incomplete resection margins had an adverse effect on survival. MEC is best managed in tertiary centres where the patients can be assessed and treated by a multidisciplinary team. © 2007 Springer-Verlag.

Publication metadata

Author(s): Chummun S, McLean NR, Howlett PC, Kelly CG, Welsh AR, Soames JV

Publication type: Review

Publication status: Published

Journal: European Journal of Plastic Surgery

Year: 2008

Volume: 30

Issue: 6

Pages: 277-282

Print publication date: 01/03/2008

ISSN (print): 0930-343X

ISSN (electronic): 1435-0130


DOI: 10.1007/s00238-007-0202-2