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Water treatment for dialysis: Technology and clinical implications

Lookup NU author(s): Dr Nicholas Hoenich

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Abstract

The dialytic process utilizes high volumes of water in the preparation of the dialysis fluid. Improvements in water treatment equipment have resulted in improvements in chemical quality. Awareness that endotoxin and bacterial fragments present in the water distribution loop within the dialysis, are able to cross the dialyser membrane, has resulted in an increased focus on this aspect of water quality. Practically, the age of many water treatment plants, extensions of distribution systems and suboptimal cleaning procedures have prevented the achievement of optimal microbiological quality on a routine basis. When achieved and maintained, clear benefits to the patient have been demonstrated. Hemodialysis patients are also subject to increased oxidative stress which may also contribute to their morbidity and mortality. Recent clinical studies using dialysis fluid made with electrolytereduced water have demonstrated benefits to antioxidant status of dialysis patients, offering a further technological solution to the problem of increased cardiovascular disease in dialysis patients. Copyright © 2008 S. Karger AG.


Publication metadata

Author(s): Hoenich N, Levin R

Editor(s): Cruz, DN; Ronco, C

Publication type: Conference Proceedings (inc. Abstract)

Publication status: Published

Conference Name: Hemodialysis - From Basic Research to Clinical Trials: 17th Annual International Vicenza Course on Hemodialysis

Year of Conference: 2008

Pages: 1-6

ISSN: 0302-5144

Publisher: S. Karger AG

URL: http://dx.doi.org/10.1159/000129724

DOI: 10.1159/000129724

PubMed id: 18451651

Notes: E-ISBN: 9783805585675

Library holdings: Search Newcastle University Library for this item

Series Title: Contributions to Nephrology

ISBN: 9783805585668


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