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Preliminary work on the development of a novel detection method for osteoporosis

Lookup NU author(s): Dr Matthew GermanORCiD

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Abstract

The novel methods of indirectly measuring bone protein structure, related to the presence of disulfide bonds were investigated. Two groups of nine subjects were identified. The Raman spectrometer was configured to analyze between 300 and 700cm-1. The results show that the lower modulii of the fingernails sourced from osteoporotic patients, coupled with decreased disulfide bond content is consistent with similar measurable structural changes within bone.


Publication metadata

Author(s): German MJ; Towler MR; Moran P; Chowdhury S; Lawson NS; Pollock HM; Saunders J; Pillay I; Lyons D

Publication type: Conference Proceedings (inc. Abstract)

Publication status: Published

Conference Name: Transactions: 7th World Biomaterials Congress

Year of Conference: 2004

Pages: 1242

Publisher: Australian Society for Biomaterials

Notes: Conference Code: 64310 Export Date: 9 October 2007 Source: Scopus Language of Original Document: English Correspondence Address: Towler, M.R.; Mat. and Surface Science Institute; University of Limerick Limerick, Ireland References: Scottish Intercollegiate Guidelines Network, , http://www.sign.ac.uk/pdf/sign71.pdf; Cummings, S.R., (1993) Lancet, 341 (8837), pp. 72-75; Marshall, D., Johnell, O., Wedel, H., (1996) BMJ, 312 (7041), pp. 1254-1259; Aaron, J.E., (2000) Bone, 27 (2), pp. 277-282; Banse, X., (2003) J Bone Miner Res, 18 (7), pp. 1247-1253; Landis, W.J., (1995) Bone, 16 (5), pp. 533-544; Stampa, B., (2002) Top Magn Reson Imaging, 13 (5), pp. 357-363; Arteaga, P.A., (1993) Tribology International, 26, pp. 305-310; Selby, P.L., (2000) Osteoporos Int, 11 (4), pp. 368-371.

Library holdings: Search Newcastle University Library for this item

ISBN: 9781877040191


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