Toggle Main Menu Toggle Search

Open Access padlockePrints

Impaired fasting glucose or impaired glucose tolerance - What best predicts future diabetes in Mauritius?

Lookup NU author(s): Emeritus Professor Sir George Sir George Alberti


Full text for this publication is not currently held within this repository. Alternative links are provided below where available.


OBJECTIVE - To determine if impaired fasting glucose (IFG; fasting plasma glucose level 6.1-6.9 mmol/l) can predict future type 2 diabetes as accurately as does impaired glucose tolerance (IGT; 2-h plasma glucose level 7.8-11.0 mmol/l). RESEARCH DESIGN AND METHODS - A longitudinal population-based study nas performed with surveys in 1987 and 1992 on the island of Mauritius, assessing diabetes status by the oral glucose tolerance test. A total of 3,717 subjects took part in both surveys. Of these subjects, 3,229 were not diabetic in 1987 and formed the basis of this study RESULTS - at baseline, there were 607 subjects with IGT and 266 subjects with IFG. There were 297 subjects who developed diabetes by 1992. For predicting progression to type 2 diabetes, the sensitivity specificity, and positive predictive values were 26, 94, and 29% for IFG and 50, 84, and 24% for IGT, respectively Only 26% of subjects that progressed to type 2 diabetes were predicted by their IFG values, but a further 35% could be identified by also considering IGT. The sensitivities were 24% for LFG and 37% for IGT in men and 26% for LFG and 66% for IGT in women, respectively CONCLUSIONS - These data demonstrate the higher sensitivity of IGT over IFG for predicting progression to type 2 diabetes. Screening by the criteria for IFG alone would identify Fewer people who subsequently progress to type 2 diabetes than would the oral glucose tolerance test.

Publication metadata

Author(s): Shaw JA, Zimmet PZ, de Courten M, Dowse GK, Chitson P, Gareeboo H, Hemraj F, Fareed D, Tuomilehto J, Alberti KGMM

Publication type: Article

Publication status: Published

Journal: Diabetes Care

Year: 1999

Volume: 22

Issue: 3

Pages: 399-402

Print publication date: 01/03/1999

ISSN (print): 0012-1797

ISSN (electronic): 1939-327X

Publisher: American Diabetes Association


DOI: 10.2337/diacare.22.3.399


Altmetrics provided by Altmetric


Funder referenceFunder name