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The structural basis of information transfer from medial temporal lobe to prefrontal cortex in the macaque monkey

Lookup NU author(s): Klaas Stephan

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Abstract

A variety of functional studies have emphasized the importance of The medial temporal lobe (MTL) and prefrontal cortex (PFC) for episodic and working memory, respectively. We investigated the structural basis of information transfer from MTL to PFC in primate cerebral cortex using the CoCoMac database (www.cocomac.org), coordinate-independent mapping procedures, and multivariate statistics. In our meta-analysis, we found a clearly decreasing gradient of MTL projections to PFC: strongest from perialloconical regions and weakest from hippocampus proper. These projections roughly divide the PFC into medial and lateral groups of areas. (C) 2002 Elsevier Science B.V. All rights reserved.


Publication metadata

Author(s): Bozkurt A, Kamper L, Stephan KE, Kotter R

Publication type: Conference Proceedings (inc. Abstract)

Publication status: Published

Conference Name: Neurocomputing: 10th Computational Neuroscience Meeting (CSN 01)

Year of Conference: 2002

Pages: 753-758

ISSN: 0925-2312

Publisher: Elsevier BV

URL: http://dx.doi.org/10.1016/S0925-2312(02)00468-X

DOI: 10.1016/S0925-2312(02)00468-X

Library holdings: Search Newcastle University Library for this item

ISBN: 18728286


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