Toggle Main Menu Toggle Search

Open Access padlockePrints

Kallmann syndrome: Adhesion, afferents, and anosmia

Lookup NU author(s): Dr Richard Quinton


Full text for this publication is not currently held within this repository. Alternative links are provided below where available.


Three new studies into the function of human anosmin-1 and related proteins in C. elegans and rodents show that these influence axon branching and axon targeting. The rodent anosmin appears to work at two stages of development, initially promoting axon outgrowth from the olfactory bulb and then stimulating branching from axons into the olfactory cortex. CeKal-1 further influences morphogenesis, and, as the human and nematode anosmins are functionally conserved, these studies provide insights into the pathogenesis of Kallmann syndrome (KS).

Publication metadata

Author(s): MacColl G, Bouloux P, Quinton R

Publication type: Review

Publication status: Published

Journal: Neuron

Year: 2002

Volume: 34

Issue: 5

Pages: 675-678

ISSN (print): 0896-6273

ISSN (electronic): 1097-4199


DOI: 10.1016/S0896-6273(02)00720-1