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Neurological and cognitive decline in adolescence

Lookup NU author(s): Dr Rob ForsythORCiD


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The evaluation of progressive neurological and/or cognitive decline poses one of the greatest challenges to the paediatric neurologist. While the potential causes are individually quite rare, collectively neurodegenerative disorders are quite common with an incidence of approximately 0.5/1000 live births.(1) Faced with an individual child, it is easy to feel daunted by textbooks' that tend to be organised according to pathology, rather than presentation, and which emphasise that many of these conditions have "variants" that can present at widely differing ages. Confusing terminologies, and non-specific presentations, tend to add to a sense of despair at ever getting to grips with the field. Confining the scope of this paper to conditions presenting in adolescence limits the number of conditions under discussion, simplifying matters considerably. However, considerations pertinent to the evaluation of progressive disease across the paediatric age range still arise.

Publication metadata

Author(s): Forsyth RJ

Publication type: Article

Publication status: Published

Journal: Journal of Neurology, Neurosurgery and Psychiatry

Year: 2003

Volume: 74

Pages: -

ISSN (print): 0022-3050

ISSN (electronic): 1468-330X

Publisher: BMJ Group


DOI: 10.1136/jnnp.74.suppl_1.i9


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