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Lookup NU author(s): Dr Rob Forsyth
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The evaluation of progressive neurological and/or cognitive decline poses one of the greatest challenges to the paediatric neurologist. While the potential causes are individually quite rare, collectively neurodegenerative disorders are quite common with an incidence of approximately 0.5/1000 live births.(1) Faced with an individual child, it is easy to feel daunted by textbooks' that tend to be organised according to pathology, rather than presentation, and which emphasise that many of these conditions have "variants" that can present at widely differing ages. Confusing terminologies, and non-specific presentations, tend to add to a sense of despair at ever getting to grips with the field. Confining the scope of this paper to conditions presenting in adolescence limits the number of conditions under discussion, simplifying matters considerably. However, considerations pertinent to the evaluation of progressive disease across the paediatric age range still arise.
Author(s): Forsyth RJ
Publication type: Article
Publication status: Published
Journal: Journal of Neurology, Neurosurgery and Psychiatry
ISSN (print): 0022-3050
ISSN (electronic): 1468-330X
Publisher: BMJ Group
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