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Profile of neuropsychological deficits in older stroke survivors without dementia

Lookup NU author(s): Dr Clive Ballard, Professor Rose Anne Kenny, Professor Raj KalariaORCiD, Dr Martin Tovee, Professor John O'Brien


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Background. Few studies have examined the profile of cognitive impairments in older stroke patients without dementia. Method. A standardized evaluation including a detailed neuropsychological assessment [Cambridge Examination for Mental Disorders in the Elderly - cognitive subscale (CAMCOG)] and computerised tests of attention and working memory from the Cognitive Drug Research battery were undertaken in 150 stroke survivors of >75 years of age and 30 elderly controls. Results: The stroke survivors without dementia had significantly greater overall impairment on the CAMCOG, as well as significantly greater impairment in memory, simple reaction time, choice reaction time (CRT), vigilance accuracy, CRT variability, spatial working memory reaction time (SWMRT) and numerical working memory than the elderly controls (e.g. CRT up arrow 33%, SWMRT up arrow 61%, memory down arrow 11%). Conclusion: Impairments of cognitive processing speed, working memory and executive functions are frequent in elderly stroke patients without dementia and represent the main cognitive components of early cognitive impairments. Copyright (C) 2003 S. Karger AG, Basel.

Publication metadata

Author(s): Ballard C, Stephens S, Kenny R, Kalaria R, Tovee M, O'Brien J

Publication type: Article

Publication status: Published

Journal: Dementia and Geriatric Cognitive Disorders

Year: 2003

Volume: 16

Issue: 1

Pages: 52-56

Print publication date: 01/01/2003

ISSN (print): 1420-8008

ISSN (electronic): 1421-9824

Publisher: S. Karger AG


DOI: 10.1159/000069994


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