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Analysis of benefit : risk ratio and mortality reduction for the UK Breast Screening Programme

Lookup NU author(s): Jonathan Beckett, Dr Colin Kotre

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Abstract

A quantitative analysis has been performed to predict the benefit:risk ratio and associated mortality reduction for the UK National Health Service Breast Screening Programme. The analysis is based on the results of an established biological simulation method coupled with dosimetric information and population statistics applicable to the UK breast screening programme. As well as the general breast screening population, the benefit:risk ratios for specific subgroups of women thought to be at higher risk are estimated. The effects of alterations in screening strategy are also investigated. The results indicate favourable benefit:risk ratios and mortality reductions for all women in the programme, with a breast cancer mortality reduction of approximately 9% over the whole UK female population, equivalent to a breast cancer mortality reduction in the region of 25% for the age range 55-69 years.

Publication metadata

Author(s): Beckett JR, Kotre CJ, Michaelson JS

Publication type: Article

Publication status: Published

Journal: British Journal of Radiology

Year: 2003

Volume: 76

Issue: 905

Pages: 309-320

ISSN (print): 0007-1285

ISSN (electronic): 0961-2653

Publisher: British Institute of Radiology

URL: http://dx.doi.org/10.1259/bjr/64009424

DOI: 10.1259/bjr/64009424

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