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Lookup NU author(s): Dr Niamh Leonard,
Dr Paul McNamara
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Malignant eccrine spiradenoma (MES) is a very rare tumor. Tumors can be low grade or high grade. There are nine cases in the literature with systemic metastases. Of these, only one was low grade; the others had obvious features of high-grade malignancy such as pleomorphism, increased mitoses, and abnormal mitoses. Low grade MESs are more difficult to diagnose and are said to have a better prognosis. We report an additional case of low-grade MES with systemic metastases. It had a monotonous appearance with few mitotic figures and minimal pleomorphism. Vascular invasion was seen in both cases of low-grade MES and may be an important prognostic feature.
Author(s): Leonard N, Smith D, McNamara P
Publication type: Article
Publication status: Published
Journal: American Journal of Dermatopathology
ISSN (print): 0193-1091
ISSN (electronic): 1533-0311
Publisher: Lippincott Williams & Wilkins
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