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Sildenafil in neonatal pulmonary hypertension due to impaired alveolarisation and plexiform pulmonary

Lookup NU author(s): Dr Christopher Wright


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We report a case of severe pulmonary hypertension in a neonate associated with impaired alveolarisation and plexiform pulmonary arteriopathy. Treatment with oral sildenafil in addition to inhaled nitric oxide (NO) resulted in recovery from the pulmonary hypertensive crisis. Long term sildenafil therapy was associated with complete resolution of the pulmonary hypertension.

Publication metadata

Author(s): Chaudhari M, Vogel M, Wright C, Smith J, Haworth SG

Publication type: Article

Publication status: Published

Journal: Archives of Disease in Childhood, Fetal and Neonatal Edition

Year: 2005

Volume: 90

Issue: 6

Pages: F527-F528

ISSN (print): 1359-2998

ISSN (electronic): 1468-2052

Publisher: BMJ Group


DOI: 10.1136/adc.2004.062885


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