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Acute renal failure due to mantle cell lymphoma - a case report and discussion of the literature

Lookup NU author(s): Dr Suren Kanagasundaram

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Abstract

Acute renal failure secondary to lymphomatous infiltration of the kidneys is a rare manifestation raer mantle cell lymphoma (MCL). We present the case of a 76-year-old gentleman with acute renal failure an a background of previously treated low grade non-hodgkin lymphoma. At the time of presentation he complained only of mild lethargy und had no lymphadenopathy or organomegaly. Renal ultrasound revealed bilaterally enlarged kidneys and renal biopsy confirmed MCL. Mantle cell lymphoma runs an aggressive course and accurate diagnosis is very important in guiding appropriate treatment. This case demonstrates the importance of renal biopsy in the diagnosis of renal lymphomatous infiltration but also highlights the potential utility of histological examination in guiding targeted therapy.


Publication metadata

Author(s): Davies J, Healey DA, Wood KM, Jones K, Kanagasundaram NS

Publication type: Article

Publication status: Published

Journal: Clinical Nephrology

Year: 2007

Volume: 67

Issue: 6

Pages: 394-396

ISSN (print): 0301-0430

ISSN (electronic):

Publisher: Dustri-Verlag Dr. Karl Feistle


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