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Clinical results with imatinib in chronic myeloid leukaemia

Lookup NU author(s): Dr Lucy Crossman, Professor Stephen O'Brien


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Since its introduction 5 years ago, imatinib mesylate has shown remarkable efficacy in treating patients with chronic myeloid leukaemia. Here we shall review the clinical results seen with imatinib at all stages of the disease, current views on the best way to monitor patients' responses and potential ways of predicting response to treatment. We shall also briefly cover the reasons why quiescent stein cells pose a theoretical threat to successful treatment. (C) 2003 Elsevier Ltd. All rights reserved.

Publication metadata

Author(s): Crossman LC, O'Brien SG

Publication type: Article

Publication status: Published

Journal: Leukemia Research

Year: 2004

Volume: 28

Issue: Supplement 1

Pages: S3-S9

ISSN (print): 0145-2126

ISSN (electronic): 1873-5835


DOI: 10.1016/j.leukres.2003.10.024

Notes: Issue title: The New Era of Imatinib Mesylate


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