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High throughput approaches in neuroscience

Lookup NU author(s): Dr Christopher Morris, Kate Wilson


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Traditional approaches to understanding biological problems are now being advanced with the use of high throughput technologies, which analyse multiple samples simultaneously, or thousands of analytes in a single sample. The application of these technologies in neurochemistry and neuroscience is beginning to be explored and is assisting in the development of new models of drug action, neuroanatomical investigations, and in identifying molecular pathways involved in neurological and psychiatric disease. Tools such as microarray-based gene expression profiling and 2D and multidimensional proteomic methods are uncovering functional components to a wide variety of neuroscience paradigms and the application of these technologies is set to become standard in analysis. (C) 2004 ISDN. Published by Elsevier Ltd. All rights reserved.

Publication metadata

Author(s): Morris CM, Wilson KE

Publication type: Conference Proceedings (inc. Abstract)

Publication status: Published

Conference Name: International Journal of Developmental Neuroscience: International Conference on Molecular Mechanisms of Neurodegeneration and Neuroprotection

Year of Conference: 2004

Pages: 515-522

ISSN: 0736-5748

Publisher: Pergamon


DOI: 10.1016/j.ijdevneu.2004.07.010

Library holdings: Search Newcastle University Library for this item

ISBN: 1873474X