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Lookup NU author(s): Dr Jonathan Smout, Professor Gerard Stansby
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Objective. To review the published evidence supporting the use of life-style modification in peripheral arterial disease (PAD). Design. A systematic search of the medical literature zoos performed for relevant studies. Materials. The publications obtained were then searched for randomised clinical trials which reported end-points Of mortality or major cardiovascular event rates with various life-style modifications. Results. Only one randomised controlled trial was found reporting relevant end-points. Other trials were of other endpoints such as walking distance or biochemical markers. Conclusions. There is a lack of randomised controlled data proving the benefit of life-style modification in improving mortality and reducing cardiovascular events in patients with PAD. Despite this there is sufficient evidence to recommend some life-style modification as part of the overall approach to risk reduction in these patients. There is compelling evidence to support smoking cessation, increased exercise and improved diet.
Author(s): Khan S, Cleanthis M, Smout J, Flather M, Stansby G
Publication type: Review
Publication status: Published
Journal: European Journal of Vascular and Endovascular Surgery
Year: 2005
Volume: 29
Issue: 1
Pages: 2-9
ISSN (print): 1078-5884
ISSN (electronic): 1532-2165
URL: http://dx.doi.org/10.1016/j.ejvs.2004.09.020
DOI: 10.1016/j.ejvs.2004.09.020
