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Lookup NU author(s): Emeritus Professor Elaine Perry,
Dr Iryna Ziabreva,
Emeritus Professor Robert Perry,
Dr Dag Aarsland,
Dr Clive Ballard
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
Choline acetyltransferase in temporal cortex was evaluated as a marker of cholinergic function in autopsied dementia cases ( 9 vascular dementia [VaD] cases, 12 "mixed" VaD and Alzheimer disease [AD] cases, 10 AD cases, 12 control subjects). Patients with AD (t = 2.5, p = 0.02) and "mixed" VaD and AD (t = 3.8, p = 0.001) had greater cholinergic deficits than age-matched control subjects and patients with "pure" VaD. The absence of cholinergic deficits in "pure" VaD may be relevant to the pharmacologic treatment of these patients.
Author(s): Perry E, Ziabreva I, Perry R, Aarsland D, Ballard C
Publication type: Article
Publication status: Published
ISSN (print): 0028-3878
ISSN (electronic): 1526-632X
Publisher: AAN Enterprises, Inc