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Modelling the disposable soma theory of ageing

Lookup NU author(s): Fotios Drenos, Emeritus Professor Thomas Kirkwood


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We describe a mathematical model. developed using the Mathematica programming system of the disposable soma theory of ageing. The model makes explicit predictions about the optimal strategies for investment in somatic maintenance versus investments in growth and reproduction and confirms the central prediction of the disposable soma theory that the optimum investment in somatic maintenance is less than what would be required for indefinite longevity. We also describe how the optimal investment in maintenance is affected by varying the parameters that specify the schedules of reproduction and mortality. (C) 2004 Elsevier Ireland Ltd. All rights reserved.

Publication metadata

Author(s): Drenos F, Kirkwood TBL

Publication type: Conference Proceedings (inc. Abstract)

Publication status: Published

Conference Name: Mechanisms of Ageing and Development: 2nd International Conference on Functional Genomics of Ageing

Year of Conference: 2005

Pages: 99-103

ISSN: 0047-6374

Publisher: Elsevier Ireland Ltd


DOI: 10.1016/j.mad.2004.09.026

Library holdings: Search Newcastle University Library for this item

ISBN: 18726216