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Lookup NU author(s): Dr Janet Berrington,
Dr Alan Fenton,
Professor Andrew Cant,
Dr Gavin Spickett
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This observational study describes the ranges observed for lymphocyte subsets for significantly preterm infants (< 32 weeks) in the first year of life, measured by single platform flow cytometry and compared to identically determined subsets in term infants. After ethical approval 39 term and 28 preterm infants had lymphocyte subset analysis before and after their primary immunization series. Median values with 5th and 95th percentiles of absolute counts and percentages are presented for total lymphocytes, T cells, NK cells, B cells, cytotoxic T cells, helper T cells, dual positive T cells, activated T cells, activated T helper cells (including T regulatory cells), pan memory T cells, pan naive T cells, memory helper T cells, naive helper T cells and the T helper/suppressor ratio. The lymphocyte profile of the preterm infants differed from that of the term infants.
Author(s): Berrington JE, Barge D, Fenton AC, Cant AJ, Spickett GP
Publication type: Article
Publication status: Published
Journal: Clinical and Experimental Immunology
ISSN (print): 0009-9104
ISSN (electronic): 1365-2249
Publisher: Wiley-Blackwell Publishing Ltd.
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