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Lookup NU author(s): Dr Mark BakerORCiD,
Professor John IsaacsORCiD,
Dr Peter Fawcett,
Emeritus Professor David Bates
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This case report is about the novel use of the anti-CD20 antibody, rituximab, in the treatment of a 41 year old woman with stiff person syndrome. She was admitted to hospital as an emergency with prolonged and painful extensor spasms affecting the neck and back, arms, and legs. The disease had progressed despite a favourable initial response to conventional treatment with intravenous immunoglobulin and cytotoxics. Treatment with rituximab induced a lasting clinical remission.
Author(s): Baker MR, Das M, Isaacs J, Fawcett PRW, Bates D
Publication type: Article
Publication status: Published
Journal: Journal of Neurology, Neurosurgery and Psychiatry
ISSN (print): 0022-3050
ISSN (electronic): 1468-330X
Publisher: BMJ Group
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