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Lookup NU author(s): Dr Richard Edwards
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Objectives. The study aimed to describe the treatment status of hypertensive patients and the prescribing patterns of private medical practitioners treating medical aid scheme patients with hypertension. Method. Data on hypertensive patients belonging to medical aid schemes were provided to the drug utilisation review consultancy, Quality Health Services(QHS), by private medical practitioners. The data were computerised and included the age and gender of the patient, the diastolic and systolic blood pressure (BP), the medication prescribed for the condition and the qualifications of the reporting doctor. All the prescribed drugs were categorised into 12 drug classes and combination preparations had each constituent categorised. The level of BP allowed the degree of BP control to be described as controlled (< 140/90 mmHg), borderline (140/90 - < 160/95 mmHg) and uncontrolled (greater than or equal to 160/85 mmHg). Results. Included in the study were 11 696 hypertensive patients (46.3% male and 53.7% female) and the 3 503 doctors who cared for them. The systolic BP showed an age-related increase, but the diastolic BP did not. The level of BP control was high, with less than a quarter of patients having uncontrolled hypertension. The most frequently prescribed drug class was angiotensin-converting enzyme (ACE) inhibitors (32.2%). Beta-blockers accounted for 20.8% and calcium antagonists for 14% of all prescriptions. Thiazide and thiazide-like diuretics on their own accounted for only 7.8% of prescriptions. However, a further 13.8% of prescriptions contained this class of diuretics in combination with other drug classes. Diuretics of all classes taken on their own or in combination were used by 33.9% of patients. Conclusions. Good levels of hypertension control were reported for hypertensive patients by their private practitioners. Almost half of all prescriptions were for the newer and more costly antihypertensive drugs (ACE inhibitors and calcium antagonists), although their effectiveness in reducing long-term complications of hypertension is still unproven. Furthermore, these prescribing patterns do not conform to those recommended by the Southern African Hypertension Society's hypertension management guidelines.
Author(s): Edwards PR, Steyn K, Walters L, Smart A, Gammon S, Lombard CJ
Publication type: Article
Publication status: Published
Journal: South African Medical Journal
Year: 1999
Volume: 89
Issue: 2
Pages: 160-164
Print publication date: 01/02/1999
ISSN (print): 0256-9574
ISSN (electronic): 2078-5135
Publisher: Health and Medical Publishing Group
