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Prevention of nosocomial infection in solid organ transplantation

Lookup NU author(s): Professor Kate Gould


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Despite improvements in survival rates, infection remains an important cause of morbidity and mortality following solid organ transplantation. Prevention of infection and, failing this, prompt diagnosis and treatment remain the cornerstones of management. During the peri-operative admission, when the level of immunosuppression is at its height, nosocomial infection accounts for the majority of infective morbidity. Although the measures taken to prevent nosocomial infection may vary, centres undertaking such procedures must ensure that strategies are in place to protect patients. The importance of basic infection control measures cannot be over-emphasised. In addition, appropriate prophylactic agents, rapid diagnostic techniques and the early institution of appropriate therapy are essential. As developments in this field advance, the epidemiology of infection will continue to change, demanding an ongoing assessment of preventative, diagnostic and therapeutic strategies.

Publication metadata

Author(s): Murphy OM, Gould FK

Publication type: Review

Publication status: Published

Journal: Journal of Hospital Infection

Year: 1999

Volume: 42

Issue: 3

Pages: 177-183

ISSN (print): 0195-6701

ISSN (electronic): 1532-2939


DOI: 10.1053/jhin.1999.0599